Our pipeline

A differentiated portfolio built for every patient journey

We are developing a portfolio of novel therapeutics targeting metabolic diseases. Substantial unmet needs persist in obesity, particularly in achieving sustained weight loss and in addressing the key underlying pathologies that impact cardiometabolic health outcomes.

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Alveus aims to address these critical issues, delivering meaningful improvements in patient outcomes.

In addition to our lead program, we are advancing an amylin pipeline of highly differentiated small molecules, peptides, and novel formats across multiple indications.

Development pipeline

A differentiated therapeutic portfolio

Alveus's pipeline is focused on next-generation metabolic therapies; the lead asset ALV-100 is currently in Phase 2. The company's preclinical amylin pipeline consists of novel peptides, oral small molecules, and other novel formats targeting improved quality of weight loss.

ALV-100 GIPR antagonism + GLP-1R agonism
ALV-200 Amylin pathway · metabolic set-point
Amylin Small Molecule Oral amylin mimetic · broad access
Fourth program Novel metabolic mechanism
Clinical trial

ALV-100 is now enrolling for the Phase 2 long-term maintenance study. Learn more about participation and eligibility.